| SANCSERV SECURITY SERVICES | Johannesburg | security services | |
| Seagorcare | Blended yarn | ||
| Sentinel Commercial Services Group | Cape Town | Business Sales and Valuations | |
| Sharp Tactical Security Sevices | Johannesburg | We provide Armrd & Un Arned Guards | |
| Shaymamba Holdings | Durban | Provides consultant services and verification | |
| Shutterbabe Snapshots | Issaquah | Photography | |
| Sikhosim Investment | BOKSBURG | Residential Rentals, Transportation, Car shuttling | |
| SimpLee VA Services | Virtual Assistant Services | ||
| Smokie - Licious Woof & Pookie Doggie Day Care | Dog Boarding/Traiining/Grooming/Walking | ||
| Somila Facilities Services | Cape Town | Professional Cleaning Services | |
| Soror Language Services - Arabic Translation | Honeydew | Soror Language Services | |
| SP Investment Holdings | Johannesburg | strategy; consulting; training and development | |
| Squeak n Kleen | Johannesburg | Home and office cleaning, Carpet and upholstery | |
| SR Communications | Durban | Business Consulting, Business Plans and Funding Sp | |
| Start a Dairy Business | chennai | Start a Dairy Business | |
| Start-Up Mentors | Cape Town | Startup: Business Coaching, Mentoring and Training | |
| Sumi Creative | Co | Artist, Designer, Furniture | ||
| The Pet Workshop | Pet Grooming | ||
| TheOfficeSupporter | Germiston | Virtual Administration | |
| Tirolite PR Events (Pty) Ltd | Johannesburg | Management | |
| Topaz Mentorship | Cape Town | Professional CV Writing | |
| Transition Online | Bedfordview | Business Consultant | |
| Tyhopo Security | Johannesburg | Guarding, patrols, armed response, access/crowd co | |
| Viatron Cleaning Services (Pty) Ltd | Cape Town | Cleaning services public, private sector entities | |
| We Buy Any Home Property Cricklewood | We Buy Any Home Property Cricklewood | ||
| WHITEDROP ENTERPRISE | Bethlehem | Consultants | |
| Xen4 | Cape Town | Coworking Office Space |
