"The transaction forms part of Aspen's communicated strategy to refine its product portfolio in South Africa," the company says in a statement.
Investors had been concerned about Aspen's debt in the last two years after levels moved close to breaching debt covenants.
That prompted Aspen to sell some of its European businesses and focus more on high margin emerging markets.
Last month the company said after its annual earnings release that it was now in a comfortable debt position.
Part of the proceeds from the sale of the portfolio, which accounted for a revenue of R512m in the last financial year, will be used to retire debt, it says.
Aspen and Acino will enter into a manufacturing and supply agreement in terms of which Aspen will supply the products to Acino for seven years, it says.
The sale excludes the cost of inventory which will be additional, the company said, adding that the transaction is likely to be completed by the end of December.
Reuters, the news and media division of Thomson Reuters, is the world's largest multimedia news provider, reaching billions of people worldwide every day.
Go to: https://www.reuters.com/
